Key Properties

• Insoluble in water and most organic solvents, but dispersible.

• pH range (aqueous suspension): ~5.0–7.5.

• High compressibility and binding ability ideal for direct compression.

• Excellent flow characteristics and tablet integrity.

• Swells and absorbs water; contributes to disintegration.

• Thermally stable up to decomposition (≈260–270 °C).

Uses

Pharmaceutical Applications

• Tablet and capsule diluent/filler – adds bulk to formulations.

• Binder – enhances tablet cohesion.

• Disintegrant – supports rapid break-up of oral solids upon ingestion.

• Direct compression excipient – widely used for simple formulations.

Other Uses (outside strict pharma)

• Food additive (dietary fiber, stabilizer).

• Cosmetic and industrial applications (thickeners, fillers).

Storage

• Store in cool, dry conditions away from moisture, heat, and direct sunlight.

• Keep containers tightly closed to prevent moisture uptake.

• Typical shelf life varies by supplier (~2–5 years under good storage).

Safety & Handling (SDS Summary)

• Non-hazardous solid under normal pharmaceutical use; no GHS hazard classification.

• Avoid inhalation of dust as it may cause mild respiratory irritation; use dust control and PPE (mask/respirator, goggles, gloves) during handling.

• May form combustible dust clouds if finely dispersed in air; implement appropriate housekeeping.

• In case of contact:

  • Skin/Eyes – rinse with water if irritation occurs. (Typical practice for inert excipients)

  • Inhalation – move to fresh air and seek assistance if symptoms persist.

  • Ingestion – generally inert; treat symptomatically.